CLSI MM22-A-2014

Clinical and Laboratory Standards Institute document MM22-A-Microarrays for Diagnosis and Monitoring of Infectious Diseases; Approved Guideline discusses the wide variety of nucleic acid microarray technologies that a growing number of clinical laboratories have adopted for diagnostic testing. The different types of microarrays and their uses in various types of laboratories have grown tremendously. MM22 specifically addresses infectious disease detection, identification, and genotyping, as well as drug resistance determinants. This guideline describes types of microarray platforms and general considerations in microarray development. It also provides recommendations for validation and verification of microarray performance and QC and QA considerations, and discusses parameters for data analysis and interpretation.