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ASTM-F2602 2008

$40.63

F2602-08e1 Standard Test Method for Determining the Molar Mass of Chitosan and Chitosan Salts by Size Exclusion Chromatography with Multi-angle Light Scattering Detection (SEC-MALS)

Published By Publication Date Number of Pages
ASTM 2008 7
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1.1 This test method covers the determination of the molar mass of chitosan and chitosan salts intended for use in biomedical and pharmaceutical applications as well as in tissue engineered medical products (TEMPs) by size exclusion chromatography with multi-angle laser light scattering detection (SEC-MALS). A guide for the characterization of chitosan salts has been published as Guide F 2103 .

1.2 Chitosan and chitosan salts used in TEMPs should be well characterized, including the molar mass and polydispersity (molar mass distribution) in order to ensure uniformity and correct functionality in the final product. This test method will assist end users in choosing the correct chitosan for their particular application. Chitosan may have utility as a scaffold or matrix material for TEMPs, in cell and tissue encapsulation applications, and in drug delivery formulations.

1.3 The values stated in SI units are to be regarded as standard. No other units of measurement are included in this standard.

1.4 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

PDF Catalog

PDF Pages PDF Title
1 Scope
Referenced Documents
Terminology
2 Significance and Use
Materials
Procedure
3 TABLE 1
TABLE 2
TABLE 3
4 FIG. 1
FIG. 2
5 Control and Approval of Data
Precision and Reporting Results
X1. RATIONALE
X1.1
X2. BACKGROUND
X2.1
X2.2
6 X2.3
X3. CONSTANT VALUES
X3.1 Calibration and Normalization of MALS-detector
X3.2 RI-detector Calibration Constant
FIG. X2.1
7 X3.3 Refractive Index Increment, dn/dc
X3.4 Second Virial Coefficient, A2
REFERENCES
ASTM-F2602 2008
$40.63